C.M.E.R. Center for Magnesium Education & Research
“CMER is dedicated to the health of humankind by promoting knowledge of nutritional magnesium and its peer-reviewed science.”

What is CMER?
CMER is a group of Independent Scholars that gathered to support one another’s efforts to promote knowledge and use of the peer-reviewed science on magnesium in medicine and health.

A Magnesium deficit can cause many symptoms associated with heart disease. When cells, tissues, organs, organ systems, and bodies have adequate Magnesium these symptoms (if due to a magnesium deficit) do not occur and the heart and blood vessels can be healthy at every level if other, non-magnesium related heart or cardiovascular issues are not present. Pharmaceutical medications that treat these symptoms are aggressively marketed and promoted despite numerous harmful side effects and long term health risks.  Since over half of U.S. adults do not take in daily magnesium adequate to their nutritional needs, it is reasonable to ask if one's heart disease risk factors might be best treated with adequate magnesium before or while resorting to these medications.

Anyone taking these medications and wanting to try a nutritional approach needs to work closely with a physician or other health professional who can guide and follow blood levels as well as cell levels of nutritional magnesium, potassium and calcium.

In general, change in medications should be done gradually and always under the guidance of a health professional.

Here are a few of the symptoms of heart disease that Magnesium deficiency causes and the types of medications that are used to treat these symptoms:


Magnesium Deficiency Symptoms                                Types of MedsTreated With                            

High Blood Pressure from too much                                    Calcium channel blockers

Calcium rushing into cells                                                          


Hyper stress reaction                                                        Beta blockers

Hyper cholesterol production                                              Statins

Blood platelet aggregation                                                  Blood thinners

Non relaxation of smc                                                        Anti-hypertensive medications such as ACE Inhibitors, Diuretics

(smooth muscle cells of blood vessels)


High Blood Pressure from

Sodium:Potassium imbalance                                            Anti-hypertensive meds, ACE Inhibitors, Diuretics

                                                                                       Low sodium, salt-restriction diets


Insulin resistance                                                              Anti-glucose meds

Arteriosclerosis                                                                 By-pass, angioplasty surgery

Susceptibility to oxidative stress                                         Anti oxidants


Can Magnesium Supplements Lower High Blood Pressure?

 Many scientific studies have been done, clinically, trying magnesium supplements' affect on blood pressure.  The results have varied widely, and until recently this was taken as an open question in medical science.  A recent comprehensive, analytic review of all of the studies shows that magnesium supplements need to be at or above the daily dose of 486 mg in people with high blood pressure who have never taken medications for hypertension or have been taking them for less than 6 months.  People with high blood pressure who are taking such medications at least six months need only take half this amount of magnesium (240 mg/day) to achieve a significant decrease in their blood pressure.  Magnesium supplements in people who have normal blood pressure will show NO CHANGE in blood pressure, i.e. magnesium will not lower a normal blood pressure as anti-hypertensive medications can.  See:  

Rosanoff, A. (2010). "Magnesium supplements may enhance the effect of antihypertensive medications in stage 1 hypertensive subjects." Magnes Res 23(1): 27-40. https://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&dopt=Citation&list_uids=20228010


Side Effects of Commonly Used High Blood Pressure Medications

Side Effects of Calcium channel blockers- Side effects of the synthetic drugs that are used as Calcium channel blockers may include but are not limited to: dizziness, headache, redness in the face, fluid buildup in the legs, rapid heart rate, slow heart rate, constipation.

Side Effects of Beta blockers- Side effects may include but are not limited to: low blood pressure, slow heart rate, heart palpitations, impaired circulation, loss of sleep, heart failure, asthma, depression, sexual dysfunction, nausea, headaches, dizziness, muscle cramps.

Side Effects of ACE inhibitors- Side effects may include but are not limited to: hypotension, cough, high blood potassium, headache, dizziness, fatigue, nausea, kidney impairment.

Side Effects of Diuretics- Side effects may include but are not limited to the loss of potassium and magnesium along with the sodium. Note: There are certain diuretics that spare potassium and magnesium. The long-term use of diuretics increases the chance of heart arrhythmia (irregular heartbeat) due to low potassium and magnesium.

Magnesium can often handle the root causes of heart disease risk symptoms and is a natural calcium channel blocker, beta blocker, statin, ACE Inhibitor and Diuretic without the harmful side effects.


Lowering Blood Pressure with Drugs Does Not Always Lower the Risk of Heart Disease

Our knowledge of the role of insufficient magnesium in cardiovascular disease tells us that hypertension, a known risk factor for heart disease, can often result from low intakes of magnesium and potassium, coupled with a high intake of sodium.

Further, the findings of many studies indicate that it is not high blood pressure per se, but rather the underlying magnesium deficiency associated with it that makes people with hypertension so vulnerable to cardiovascular disease. Correcting high blood pressure without correcting an existing magnesium deficiency may not prevent cardiovascular disease. It may even make things worse if side effects of medications or the high stress due to an individual’s inability to make prescribed dietary and lifestyle changes end up increasing the severity of the underlying nutritional deficiency.

Please help us continue our work.

The Magnesium Factor:
How One Simple Nutrient Can
Prevent, Treat, and Reverse
High Blood Pressure, Heart
Disease, Diabetes, and
Other Chronic Conditions